美首次发现对抗生素产抗药性超级细菌(201695271112)z

美国境内首次发现对所有抗生素产生抗药性的超级细菌。
美国疾病控制与预防中心官员表示,携带超级细菌的是一名来自宾夕法尼亚州的49岁妇女。她因为尿道感染而入院治疗。医生在她的尿道内发现的大肠杆菌对所有抗生素产生抗药性。
卫生官员说:“染病的妇女不曾出国,因此不可能在国外感染超级细菌。”
卫生官员表示严重关切,指一旦超级细菌传播,可能造成严重危机。
美国疾病控制与预防中心主任弗里登警告,事件反映抗生素治疗已到尽头,有必要采取紧急行动。
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17 个回答

洪生维

楼主的那个新闻更是特例哦!
美国对抗生素使用的管制很严的,这种特例既然发生在美国,说明和抗生素滥用无关。要是发生在中国,还可能是抗生素滥用造成的。

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洪生维

都是好的为啥开抗生素?
这种剂量的抗生素是治疗肺炎时才需要的啊

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冉辰钧

昨天带两岁女儿去KK
也是感冒了,但是验血,x光都是好的,医生没办法开了抗生素,阿莫西林,我想知道你当时开的大剂量是多大, 我总觉得给我2岁不到女儿一天三次,一次12.6ml真的太多了,还要吃7天

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荣若晨

+1
正解

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燕融

楼主转载的中文版有误,请不要以讹传讹……
并不是对所有抗生素有抗药性,carbapenem还是可以用的,文章重点是说对最后一道防线抗生素colistin有抗药性
这个colistin抗药性基因叫mcr-1,这是美国国内第一次发现含有这个基因的细菌,但是并不是全世界第一次,mcr-1早就在其他国家出现了,尤其是中国!!
mcr-1基因可以通过质粒在细菌之间传播,mcr-1的发现预示着“真正的超级细菌(无药可治)”也不远了……
另外文中提到的女病人并不是从没出过国,只是过去5个月没有旅行记录而已……


以下是Medscape上的英文版

First US Case of E coli Resistant to Last-Resort Antibiotic

Researchers have spotted the first known instance of bacteria impervious to the last-resort antibiotic colistin in the United States, exacerbating fears of superbugs that can turn an ordinary infection deadly.
The case involves a 49-year-old woman treated at a clinic in April for a urinary tract infection. A urine culture revealed a strain of Escherichia coli that was later found to be resistant to colistin. The findings were published online today in Antimicrobial Agents and Chemotherapy.
In a speech at the National Press Club today, the head of the Centers for Disease Control and Prevention (CDC) said the study is a call to develop new antibiotics and use them wisely.
"The medicine cabinet is empty for some patients," said CDC Director Thomas Frieden, MD, MPH. "It is the end of the road for antibiotics unless we act urgently."
What is even more alarming about the case of the Pennsylvania woman is that the E coli became resistant to colistin not through mutation, but by acquiring a snippet of DNA called a plasmid that carries the resistance-conferring gene. Such plasmids easily spread from bacterium to bacterium.
"The recent discovery of a plasmid-borne colistin-resistance gene, mcr-1, heralds the emergence of truly pan-drug resistant bacteria," write the authors, all associated with Walter Reed National Military Medical Center in Maryland.
Although the authors say this is the first report of mcr-1 in the United States, the colistin-resistance gene has surfaced in bacteria in other countries, notably China.
The Pennsylvania woman had not reported any travel during the previous 5 months. The study does not describe her current condition.
"Continued surveillance to determine the true frequency for this gene in the USA is critical," the authors write.
In his speech today, Dr Frieden described colistin as the only antibiotic left "for what I call the nightmare bacteria, carbapenem-resistant enterobacteriaceae (CRE)."
It turns out that the Pennsylvania woman''s infection was not resistant to carbapenem antibiotics, another CDC official told Medscape Medical News. However, Christopher Braden, MD, deputy director of the agency's National Center for Emerging and Zoonotic Infectious Diseases, warned that the plasmid-borne colistin-resistance gene could transfer to CRE or any other superbug, making them deadlier.
The CDC and the US Department of Defense are working with the Pennsylvania Department of Health (DPH) to investigate the case of colistin-resistant E coli, according to a DPH news release. The DPH said that state law prevents it from disclosing specific details about the inquiry or the patient.

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燕融

另外你的逻辑很奇葩
中国滥用抗生素没有发现超级细菌,而美国管制抗生素却发现了超级细菌,所以说明超级细菌的产生跟滥用抗生素无关?
那么跟什么有关?风水吗?呵呵

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燕融

你这话就纯属无理取闹了
你也说了,现在得了肺炎只要及时使用抗生素就没事了,那是因为抗生素可以杀死感染的细菌
可是如果感染的是超级细菌,那么现有的所有抗生素都没用了,就好像回到一百年前还没发现抗生素之前的时代……

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燕融

请注意,美国第一次发现并不代表超级细菌只出现在美国
细菌有没有抗药性要做culture and sensitivity才能知道,而c/s并不属于routine test,一般在病情比较严重时医生才会order c/s,中国没发现并不代表中国一定没有超级细菌,有可能某些病人已经死于超级细菌感染了,只是因为没有做c/s不知道罢了……就算现在没有也不能保证以后一直没有,细菌不断产生抗药性已经是全球趋势了

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洪生维

还有
正常人,尤其是小孩,得了肺炎如果不及时用抗生素治疗,死亡率也是很高的。。。

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洪生维

卫生官员又在危言耸听
凡事物极必反

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